FPM 237 Microarray Technology and Informatics 2010
Winter 2010, Division of Biostatistics and
Bioinformatics, Department of Family & Preventive Medicine School
of Medicine Elective Course
Organizers:
- Sonia Jain, Ph.D., Div. of Biostatistics and Bioinformatics, Dept. of Family & Prev. Medicine
- Gary
Hardiman, Ph.D., Div. of Endocrinology & Metabolism, Dept of
Medicine and Director of Biomedical Genomics Microarray Facility
Time: Thursday 3:00—5:00 p.m.
Room: Leichtag Building, Room 2A05
Units: 2 units
This 9-week course is an introduction to DNA microarray technology
and methods to analyze gene expression data. Topics will include
platform types, image processing, experimental design, statistical
analysis, and applications in medicine and the health sciences.
Prerequisites: There are no formal prerequisite courses.
Recommended Textbooks: A list of recommended textbooks and articles will be provided at each lecture.
Course Content: Content and emphasis
of the course is defined by lecture material. It is important to attend
all lectures as there is normally no way to make up for missed lectures.
Course Materials
Evaluation: The grading for this course is "s/u only". The grade will be based on class participation and a term project.
Lecture Schedule:
-
- January 7 -- Microarray Expression Platforms and Formats (Bhasker)
- January 14 -- Protein Arrays (Bhasker)
- January 21 -- Experimental Design (Jain)
- January 28 -- Data Preprocessing and Normalization (Topher Woelk)
- February 4 --Classification and Cluster Analysis (Topher Woelk)
- February 11 --Methods for Determining Differential Gene Expression (Chuck Berry)
- February 18 -- Alternative Arrays: SNP arrays, micro-RNA arrays (Hardiman)
- February 25 -- Microarrays - Past, Present, and Future (Hardiman)
- March 4 -- Microarray Applications in the Health Sciences (Nik Schork)
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